This T-cell receptor helps to activate both cytotoxic T-cells (CD8+ naive T-cells) and T helper cells (CD4+ naive T-cells). Present as a protein complex, it comprises 4 distinct chains. In mammals, this complex contains a gamma, delta and two epsilon chains.The CD3γ, CD3δ and CD3ε chains are highly related cell-surface proteins and contain a single extracellular immunoglobulin domain.

        该T细胞受体有助于激活细胞毒性T细胞（CD8 +幼稚T细胞）和T辅助细胞（CD4 +幼稚T细胞）。以蛋白质复合物状态存在，它包含4个不同的链。在哺乳动物中，该复合物含有γ，δ和两条ε链。CD3γ，CD3δ和CD3ε链是高度相关的细胞表面蛋白，并含有单个细胞外免疫球蛋白结构域。

 

         CD3 antigen can be found bound to the membranes of all mature T-cells and in virtually no other cell type. This high specificity, combined with its presence at all stages of T-cell development makes it a useful T-cell marker for IHC tissue sections. The antigen is also present in almost all T-cell lymphomas and leukaemias, allowing their differentiation from similar B-cell and myeloid neoplasms.

         可以发现CD3抗原与所有成熟T细胞的膜结合，而且实际上结合的没有其他的细胞类型。这种高特异性与其在T细胞发育的所有阶段的存在相结合，使其成为IHC组织切片的有用T细胞标记物。抗原也存在于几乎所有T细胞淋巴瘤和白血病中，允许它们从类似的B细胞和骨髓肿瘤中分化。

 

         Biorbyt has a highly validated and comprehensive range of CD3 proteins, antibodies and genes including the difficult to source Biotinylated Human CD3 epsilon and Human CD3E & CD3D heterodimer protein. We also offer the hard to find Mouse CD3 epsilon protein.

          Biorbyt拥有高度验证和全面的CD3蛋白，抗体和基因，包括难以获得生物素化的人CD3ε和人CD3E和CD3D异二聚体蛋白。我们还提供难以找到的Mouse CD3 epsilon蛋白。

Our favourite and most unique products are highlighted below:

MAb to CD3

PAb to CD3

CD3 Proteins

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